NEW RESEARCHES UPON PLEURO-PNEUMONIA, ETC. 463 
The serosity which escapes from the divided lung of a cow 
affected to the first or second degree of the disease, and sifted or 
filtrated, is the best to use in the practice of inoculation and 
should be inserted on one of the lateral faces of the extremity of 
the tail, by two punctures with a lancet, about the width of two 
or three fingers apart. The operation is made like vaccination, by 
incision of the epidermis and deposit of a drop of vaccine in the 
cellular tissue and in the dermis ; the animal is then left to itself 
without any other care. It is prudent, however, to give him a 
good clean bed, to protect the wound from infection by contact 
with decomposed matters. 
The liquid of inoculation must be as fresh as possible, as I 
have often observed that the one, two, or three days old is very 
virulent. 
When the local inflammation becomes too active, a purgative 
is administered ; three or four hundred grams of sulphate of mag¬ 
nesia. 
When there appears at the point of inoculation a hard, warm, 
inflammatory swelling, painful to pressure, we must hasten to 
make incisions, and to excite suppuration by local irritating 
agents, for as soon as this is obtained we may be sure that the 
infiltration will not spread ; and the animal is saved. 
Some operators remove the portion of the tail above the 
swelling, and others cut always, to prevent the local accidents 
which may take place twenty-four hours after the operation, the 
portion of the tail where the inoculation has been performed. 
If, from fifteen days to three weeks after the operation, no 
appreciable effect at the point of inoculation is observed, it is well 
to have recourse to a re-inoculation. 
When the disease appears in a stable it is necessary to isolate 
the animals yet apparently healthy, and to inoculate them at once, 
using, for this, the serosity of the lungs of one of the diseased 
animals killed at once. 
No fresh, sound animals ought to be introduced into infected 
stables without having them thoroughly disinfected, as without 
this precaution the newly arrived animals would be brought im¬ 
mediately under the influence of contagion, and the disease would 
