NEW RESEARCHES UPON PUEURO-PNEUMONIA, ETC. 511 
I feel obliged to recall the first researches made upon these 
germ corpuscles by Mr. V an Kempen, the distinguished professor 
of pathological anatomy in the University of Louvain, and by 
myself. 
I said : “ I have examined different pathological portions, for 
the purpose of studying and elucidating the question of inocula¬ 
tion. My investigations have principally been of diseased lungs 
and upon a form of tubercle, unrecognized till then, but that I 
have, however, constantly found in the autopsies made upon ani¬ 
mals which had died with pleuro pneumonia. The tubercles 
which spread in all the intestines, especially the small, were of a 
size varying from that of a pin-head to that of a large pea, being 
of a yellowish or greenish color, and situated in the sub-mucous 
cellular tissue, and partly in the thickness of the intestinal mem¬ 
brane. They seem to have no link of origin with Peyer’s or 
Brunner’s glands. Are they hyperhophied follicles ? Nothing 
seems to prove it; they show no openings. They are formed of 
an homogeneous whitish matter, more or less hard, presenting un¬ 
der the microscope granular nuclei and a large number of small 
elementary corpuscles, which have a molecular motion, and which 
are also found in the diseased lungs, as I will show further on. I 
have subjected parts of lungs of pneumonic animals to the micro¬ 
scope, with a magnifying power of 540 diameters; much greater 
than that of the one used by Prof. Gluge in his handsome anato¬ 
mico-pathological researches upon pleuro-pneumonia. The exu- 
dated matter presented no structure; I have found in it no 
other anatomical elements than granular nuclei and elementary 
corpuscles with a peculiar motion, the whole having a strong re¬ 
semblance to an inflammatory exudate, remarkable for its great 
quantity. The plastic exudations are formed so rapidly and in 
such quantity, that anatomical elements of a higher development 
than that of these nuclei cannot form themselves; consequently 
there are no cells, no pus corpuscles, (I found none) no fibrios. 
The strength of the cellular tissue seems to exhaust itself on too 
large a quantity of exudated matter, for this to reach a higher 
degree of organization. It is as one observes it sometimes in the 
regeneration of tissues; for instance, in the section of nerves and 
