514 
DR. WILLEMS 
in them the molecular motion spoken of by Willems; still, its ab¬ 
sence is of no value and ought to be considered only as simple 
browmian motions, manifest in all the corpuscles of extreme small 
size, when, freed from all attachment, they float in a liquid. This 
last condition was entirely absent in the present case, for the 
reason that the granules were surrounded by a great quantity of 
coagulated fibrine, infiltrated in the pulmonary tissue. 
“ Mr. Willems asks if these granules are primitive or secondary 
in the disease ? 
“ Considering that like corpuscles, with a similar peculiar mo¬ 
tion, are seen in the larvre of the lepidoptera in pathological con¬ 
ditions, especially in the muscardine of the silk worm, and specially 
in the butterfly, when it dies a natural death, from which comes 
the probability that those are an effect rather than the essential 
cause of the condition which naturally brings on death after a 
short time in perfect insects, and again noticing that, in the 
given case, these corpuscles were in quite large number in spots 
deeply altered, that they were gradually diminishing, leaving 
these spots by degrees, and they were not found in the parts of 
the lungs which had retained their normal aspect, one is, there¬ 
fore, disposed to consider them more as secondary than as prim¬ 
itive in the disease.” 
Since that period the study of these corpuscles has been dis¬ 
continued, until in later days it was resumed by me. 
Wishing to have the correctness of my remarks confirmed, I 
asked one of the members of the Academy, Mr. Cousot, whose 
studies lie especially in that direction, and two specialists of the 
University of Louvain, Prof. Yerriest and Bruylandt, to assist me. 
This they willingly consented to do and I wish to present here 
my public thanks for their courtesy. With me my worthy col¬ 
leagues have recognized the existence of the microbe of the 
parasite in question, and its culture by Pasteur’s processes has 
been effected by them with complete success to the eighth genera¬ 
tion. 
This intervening microbe is treated with all the caution re¬ 
quired by its importance, and in the liquid of culture most often 
selected, it grows in innumerable quantity and appears exceed- 
