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BIBLIOGRAPHY. 
cute or open on a common yard, and lias almost always spread 
when stables are separated by a wall. 
In infected stables where Inoculation of healthy animals has not 
been done , never did the disease stop after one single victim. 83 
per cent, became pleuro-pneumonic. 
In infected' stables where healthy animals were inoculated,, fre¬ 
quently the disease stopped entirely. When it continued, the 
mortality was much reduced. 
Inoculation has been followed by valuable preventive effects 
only when practiced from the time of the first case of sickness 
seen in the stable. 
The virus produced by the first pleuro-pneumonic cow is ab¬ 
sorbed first by one, two, seldom three others, which, in their turn, 
produce and exhale the virus, which gives rise to a new series of 
victims. The effects of the virus are visibly manifested after 
about three weeks; there is then pulmonary hepatization. In 
practising inoculation, it prevents hepatization, in a manner we 
cannot explain. Inoculation done during the latent period, or 
when the disease manifests itself externally, has not stopped the 
disease. 
In non-infected stables, we never introduced the disease by inoc¬ 
ulation. 
Inoculation can be performed at all times. 
The most ordinary consequences of inoculation are : 
(a), Limited swelling of the tail, round the wound, which gives 
rise, often a long time after, to purulent discharge ; (b), frequently 
general functional disturbances. 
Sometimes the swelling did not appear, even when the inocula¬ 
tion was repeated. Bovine, under these conditions, are refractory. 
Exceptionally, we have had an excessive swelling, extending 
above the base of the tail. This always subsided by surgical and 
medical attention. Not one animal has succumbed to it. 
Finally, inoculation is indispensable to protect bovines , which 
have cohabited with or near others affected with pleuropneumonia ; 
that is to say , which have been , or may have been exposed to the 
influence of the virus, providing it is performed at the moment 
the animals have been exposed to the virus. 
