TRANSLATIONS FROM FOREIGN PAPERS. 
365 
course, the blood was poor in virulent matter. It was known 
long ago that, to succeed in inoculating sheep with small-pox, or 
even vaccinate children, the serosity must be clear and not mixed 
with blood. This last liquid was never to be used exclusively. 
The experiments of M. Chauveau have then well confirmed 
the facts obtained by clinical observations. 
A second paragraph of bis memoir relates the numerous 
experiments of sub-epidermic inoculation, always followed by 
success upon animals subject to the disease. The mode is, conse¬ 
quently, not only the simplest but the surest. At this point, M. 
Chauveau observes that sometimes and frequently upon very 
young subjects, the local is accompanied by a generalized eruption, 
and as proofs of the correctness of this opinion be cites two well 
demonstrated cases. 
Though hesitating to differ in opinion with such an expert and 
distinguished experimenter, I must say that 1 have always seen 
the eruption generalized on animals affected for the first time. 
It is more or less abundant and easily seen, but never missing. 
As well as in inoculating the small-pox to sheep, the distemper 
to pups, and even variola to man, one communicates to the inoc¬ 
ulated individual a general affection, as well by the inoculation of 
its variola proper or horse-pox, one gives to the horse a disease 
whose eruption is not limited to the points of inoculation. 
I will return to this question later. For the present it is well 
admitted that inoculation performed upon a healthy animal gives 
him surely the disease. Incontestable and iiicontested fact. 
As to the effect of inoculation upon animals previously affected, 
it is generally negative. In the cases where it is positive, it is 
only when the first attack took place for some time past, and 
yet the development of the pustules is limited to the points where 
the virus has been applied. I have often tried to inoculate a 
second time a horse which had already been so treated several 
months previous. It would, however, be an error to believe that 
this recidive cannot take place. M. Chauveau cites several exam¬ 
ples. All veterinarians have seen it, and for myself I have 
succeedeed in obtaining handsome pustules on a five years old 
horse, which I inoculated also successfully when one year old. 
