8 
affected in several different ways, the same as I described in my 
pamphlet years ago, some showing symptoms of Paraplegia (Paralysis 
posterior extremities) most were of this variety, some were first 
attacked in the throat, paralysis of Pharynx (not sore throat) as shown 
by the water test, the manner of drinking I pointed out long ago, 
a few were first attacked in the head, manifesting brain symptoms. 
When taken on the road, some cases were marked simply by muscular 
tremors of different parts, (many of the fore extremities) others by 
symptoms of Colic, before the more direct symptoms manifested them¬ 
selves. Those in the stables, with the paralytic symptoms of the part 
first, attacked as previously alluded to head, throat or loins, with all 
was obstinate constipation (faeces, hard, dry, and coated with mucus, 
when removed by hand). One case had violent tonic spasm of all 
muscles posterior to lumbar region. 
Pulse in all cases, but little affected in number and compressible ; 
temperature, except in cases already noted, one to two degrees above 
normal. 
Treatment .—Powerful purgatives to overcome constipation, to try 
and wash out of the system some of the poison; relieve the bloodvessels 
by a serous bleeding; relieving blood pressure, passive congestion of ves¬ 
sels, and prevent escape of contents under the membranes; the use of 
Belladonna to stimulate the paralyzed sympathetic. I believe Bella¬ 
donna one of the most powerful nerve stimulants we know of, particu¬ 
larly to the sympathetic acts on the walls of the small vessels constrict, 
and regulates the circulation through them. In cases wheie the heart s 
action was weak, Ammonia in conjunction, or if throat was affected, 
and swallowing was difficult as it would be dangerous to administrate 
medicine by mouth, Atropine was injected hypodermically, and 
whiskey in gruel given per rectum. All the unaffected horses weie 
placed under the action of Belladonna, and all cases kept under its 
influence for nearly tw r o weeks, though having so many cases, I did not 
push the drug as I safely could have done, to three times the amount 
given if I could have closely observed each case myself. I gave strict 
orders about fumigating and disinfecting ; chloride of lime, carbolic 
acid, and burning tar were freely used. I also directed close attention 
to ventilation, which I am sorry to say, was not closely observed at 
first, for I found in spite of treatment more fresh cases (from 10 to 15 
a day) were occurring than I had a right to expect, although the 
weather was truly March the entire tw T o v r eeks, with the exception of 
three days, I knew there was something wrong, so on the fifth night, 
I should have done it before, T paid a visit about 10 I. M., and found 
all the doors, wdndows and ventilators closed tight, the stench was 
abominable, the air stifling. 1 was surprised then v^e had managed 
as well as we had. I personally superintended the opening of the 
