134 
PROF. COLIN. 
aorta,, upon which passes the diseased nerve. It is the same nervous 
lesion that is found in roaring. 
The most important lesions are those of the vagina. They con¬ 
sist in two large circular ulcerations, irregular, and situated, the first, 
at the internal face of the left lip, near the inferior commissure; the 
other below and near the urinary me*atus. They constitute an ex¬ 
ceptional peculiarity, as they have not been described before. 
1 he examination of the blood, incompletely made, shows a state of 
glanderous leucocythosis, well marked. 
Though this animal suffered with latent glanders, in the full sense 
of the word, the nasal lesions were not entirely missing, but, on one 
side, they are very deeply situated on the septum, near the ethmoid, on 
a point impossible to reach with the eye or the finger. They are rudi¬ 
mentary and very recent. They consist in two or three small round 
nodules, hard, not ulcerated j and for this condition do not give rise to 
the characteristic discharge, nor to the tumefaction of the ganglion. 
Taking all the lesions in consideration, the development of the dis¬ 
ease can be divided into three periods. 
1 he pulmonary lesions, well marked, are undoubtedly the oldest. 
They indicate the first age of the disease, which may have lasted very 
long, and comprehend several stages of development of infarctus, pseudo 
tubercles, and abscesses. d he lesions of the trachea and larynx are 
more recent, representing the second age—the period of transition. 
The nasal lesions form the third stage. If the animal had lived 
several weeks or months more, the discharge following the ulceration of 
the pustules, the swelling of the glands, would have constituted a fourth 
period of that disease. 
As conclusion, Mr. Colin asks : “ If many cases of glanders, which 
seem to make their appearance suddenly, are not, properly speaking, old 
cases, which had remained latent for a period of various duration before 
arriving to the form, where the nasal characteristic symptoms are well 
developed.” 
If the ordinary forms of glanders are mostly cases of latent diseases, 
or glanders already existing in the lungs, trachea, larynx, before the 
eruption of nose, the discharge and ganglionar swelling.” 
“If the leucocythosis would not be the most positive means of diag¬ 
nosticating the disease in case of latent form, and as long as the 
symptoms of the affection are not sufficiently characteristic.” (Archives 
Veterinaires.) 
