220 
A. LIAUTARD. 
cessive. I have seen, in a certain number of experiments, healthy blood, 
placed in not compressed oxygen, take a peculiar odor which was not 
that of putrefaction, and still when inoculated in quantity smaller than 
a drop, to kill rapidly by septiaemia. 
Then, if this blood thus placed in oxygen had been carbunculous, 
as putrefaction destroys its special virulency, as I proved it, one would 
have produced by inoculation with it, not anthrax, but septiaemia. 
I mention these results, not to come to any conclusion of the not 
compressed to the compressed oxygen, but to call attention to facts 
which may have some importance to the point of view of the effects of 
compressed oxygen upon carbunculous blood. 
I will now add a few words relating to a question of Mr. Bouley 
upon the pathogeny of some forms of anthrax diseases. 
I he observations and the experiments I have made upon this sub¬ 
ject have allowed me to establish that the pustula maligna form, almost 
special to man, is produced by the introduction of the virus under the 
epidermis, in the reti mucosum of the skin, and that the sub-cutaneous 
tumors, so common in horses, are produced by the introduction under the 
teguments of a fraction of a drop of infected blood. I have shown how- 
flies may, in the country, become the true agents of these two modes of 
inoculation. 
Carbunculous fever without external manifestation appears, when 
substances impregnated with virus are introduced in internal organs. 
As f° r the tumors, called critical , which develop themselves during that 
febrile disease, and as an effort of the medicating nature which carries 
the virus under the teguments so as to expel it, I have never observed 
anything like it. In my opinion, itTs an old error, due to a false inter¬ 
pretation of the course of the disease. Indeed, the bacteridies, motion¬ 
less, cannot spontaneously quit the organs to go in a fixed region of the 
body; and, besides, the economy of the patient cannot collect together 
these millions of small beings located all over, and direct them towards 
a special point of the organism. 
To accept such a result, we must suppose a kind of filtration, and of 
a special circulation madmissable to physiology; and to effect that it 
seems to me certain that these, so-called, critical tumors were primitive, 
and not consecutive to the invasion of the disease ; they are formed 
where the virus has been introduced from outside, and it is because they 
1 emain yet localized that the surgeon will sometimes cure them. 
