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from the disease when confined in the same stable with vaccina- 
diseased cows, and inoculations with the latter generally give only 
a negative result; therefore the disposition of goats for vaccine 
or better, for the eetiological agent of the same, is in all cases in¬ 
significant. 
As a severe and general disease—although seldom—we meet 
witli variolse by goats which are confined in the same stable with 
variola-diseased sheep. In the place of further description, I quote 
a recent observation: “In a stable in which variola-diseased 
sheep were confined, three non-inoculated goats became suddenly 
diseased with variola, the exanthema of which exactly corresponds 
that of v. ovina. Upon the udder were to be found numerous 
pisiform variolse in the form of hard flattened noduli, with little 
exudation of lymph; aside from these were to be seen variolic dis¬ 
tributed over the body, especially upon the median face of the 
posterior extremities, more isolated upon the abdomen, along the 
back and on the head. At the same time marked fever phenom¬ 
ena were present, the appetite failed, the lips were tumefied, a tol¬ 
erably profuse muco-purulent flow was perceptible from the nasal 
cavities. Convalesence resulted in 14 days. Immediately on 
these goats becoming diseased, two others were inoculated upon the 
ear witli ovine ; by both a single inoculatory pustule developed, 
and both remained immune from v. ovina vera. Prietzscli. 
From the above, it may be seen that v. ovina may be accident¬ 
ally transmitted to goats; also that positive results follow the 
inoculation of the same with ovine. As we have seen, the so- 
called caprine variola owes its genesis either to v. ovina or to v. 
vaccina, or finally it may sometimes be traced to the same fountain 
of infection as the latter, and is homologous to the same. 
With regard to the variola by other domestic animals, the 
data before us are so scanty that it is with difficulty that we can 
draw anything positive from them. Although in most Manuals 
of Pathology v. canina is described, yet I must say, that I have 
been successful in the new literature in finding but one de¬ 
scription, that will allow us safely to deduce that by dogs a true 
variolous eruption takes place. Authors have attributed to such 
true canina variola, either an epigenetic origin, or traced the 
