LOCAL SPECIFIC THERAPY OF INFECTIONS 
115 
hand of antipneumococcal sérum [15] and on the other of 
optochin [16]. Experimental slreptococcal inlections of the 
utérus inrabbits hâve heen controlled by the local application 
of antistreplococcal sérum [17]. A mere beginning has been 
made in thi's üeld of investigation ; with growlh of knowledge 
of the spécifie qualities of microôrganisms, as determined first 
by species and next by variants or mutants, and ever finer 
approximation between the pathogenic microbe and the 
spécifie antidote designed to overcome ils pathogenic effect will 
be sougbt. Undoubtedly antisera are capable of doser adapta¬ 
tion in this respect ; but an outlook even more promising is 
afforded by experimental chemo-tberapy since spécifie drugs 
already appear to be less narrowly limited in their activities 
by the finer antigenic distinctions occurring among the variants 
of a single microbic species. 
It is profoundly gratifying that immunology, to wliicb subject 
professor Metchnikoff, whom we today honor, contributed the 
fundamental and fertile doctrine of phagocylosis, should liold 
out such high h opes of benefit to mankind. 
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