various drugs, hookworms passed as follows: First day, 74.1 per 
cent; second day, 15.7 per cent; third day, 7.4 per cent; fourth day, 
2.8 per cent. Efficacy of carbon tetrachlorid, approximately 100 per 
cent. 
Whipworms. Santonin, 0.5 to 1 grain, with an equal amount of 
calomel daily, two to three hours before feeding in the morning, for 
one week. Suspend treatment for one week, and then repeat for a 
week. The results should be checked by examination of the feces 
for worms passed and for eggs persisting, to make sure of the re¬ 
sults, but this makes a fairly satisfactory routine treatment where 
such examinations cannot well be made. The difficulty in removing 
whipworms is due to the fact that drugs do not always enter the 
cecum after passing the ileo-colic valve. Even relatively feeble 
anthelmintics will remove whipworms when they enter the cecum. 
Entrance into the cecum can be ensured to some extent by using 
repeated doses or very large doses. For repeated doses a non-ir¬ 
ritant drug, such as santonin, is distinctly indicated. If large doses 
are to be employed, it is advisable to use a drug of low toxicity and 
a high safety factor, such as carbon tetrachlorid. Carbon tetrachlorid 
in one large dose, 1 cc. per kilo, will sometimes prove effective in re¬ 
moving whipworms. Strong animals will tolerate this dose or much 
larger doses, but it is inadvisable to use large doses of anthelmintics 
in the case of old, very young, or sick or weak animals. 
Tapeworms. Fast overnight. Arecoline hydrobromid by mouth, 
Vi grain to small dogs; grain to dogs of average size. No purga¬ 
tive; the drug itself is purgative. Worms usually pass in half an 
hour, but tapeworms of the genus Dipylidium may pass for four days 
after tapeworm treatments, the worms in a series of experiments 
coming away as follows: First day, 91 per cent; second day, 7.4 
per cent; third day, none; fourth day, 1.6 per cent. This tapeworm 
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