— 4 §o — 
and the lips and fingers trembled constantly. The appetite was 
irregular, the digestion poor, and the bowels constipated. There 
were ni signs of rheumatism. The examination of the blood was 
négative for parasites; she had recently been takink « chill-tonic ». 
The red cells numbered 3.950.000, the whites 7.900. There was 
an almost entire absence of platelets. The hemoglobin was esti- 
mated at 60 % (TalqüiST). The differential leucocyte count was ; 
small mononuclears 25 %; large mononuclears 14 %; polymor- 
phonuclears 51 %; éosinophiles 10 %. The treatment prescribed 
consisted of a teaspoonful every four liours of an élixir contain- 
ing five grains of calcium chloride to the dram, besicles an anti- 
malarial tonie of strychnine, arsenic, iron and quinine* Within 
a week ail purpuric spots had disappeared excepting a large ec- 
chvmosis on the left forearm. On May sotli. the hc-moglobin was 
100 % though the spleen was still considerably enlarged ; she 
lias had no chills nor purpuric symptoms up to this date which 
is the longest interval free from chills she has enjoyed in several 
years. 
Marchiafava and Bignami (i) call attention to the importance 
of differentiating these cases from acute leukemia. They saw a 
case of acute leukemia in a young girl who had purpuric skin 
with hemorrhages from the gums, stomach, genitals, and else- 
where, in which hémorrhagie malarial infection had been dia- 
gnosed on the strength of an irregular température and an enlar¬ 
ged spleen. The microscopie examination of the blood revealed 
the true condition. 
Fièvre spirillaire en Abyssinie 
Par P. DOREAU. 
M. E. Brumpt a communiqué à la Société de Pathologie Exo¬ 
tique, dans sa séance du 8 juillet dernier, un cas de transmission 
expérimentale de Spirilles à un singe, le Macacus rhésus, par des 
(1) Marchiafava and Bignami, Malaria, New-York, 1900. 
