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titis, with ulcération of the labial and lingual mucous membrane; 
gastritis, frequently with ulcération of the abomasum ; enteritis, 
and often a marked proctitis are the main lésions présent. Ex¬ 
cessive lachrvmation and a muco-purulent discharge from the 
nostrils are usuallv pronounced clinical svmptoms, together with 
a foeticl diarrhoea often containing blood and mucus. 
Tn young calves the disease frequentlv runs its course in three 
to five davs after malaise is first noticed bv the owner : in older 
animais seven to ten davs would be an average duration. The 
mortalitv is usuallv not more than lo % to 20 % of sick animais, 
and it the young and the old which principally succumb. In af- 
fected herds up to 90 % may be attacked, but on some farms onl)- 
one or two animais bave shown visible svmptoms. Towards the 
termination of the disease a drv scaly éruption appears on the 
neck and shoulders, and in some cases extends over the whole 
surface of the bodv and mai^ be accompanied by considérable 
thickening of the epidermis and bv shedding of the hair. In 
chronic cases, and these are not rare, the duration ma}^ be of 
several months, with anaemia as the most common symptom. 
Prior to the discoverv of Coccidia in these cases, experiments 
had been instituted at Kisumu, a heavilv infected district on Lake 
Victoria. Three sets, each of two animais, were employed. A ser- 
ved as Controls and had full contact with the sick animais and 
the infected pastures; B had co^ntact with the sick, but were muz- 
zled and were fed onlv on grass imported from a clean area (Nai¬ 
robi), and were given onlv water which had been boiled ; C were 
kept witchin a fenced Amrd in the centre of the infected pasture, 
and were there given the same grass and water as were eaten and 
soiled bv the sick. At no time did these C animais corne into ac- 
tual contact with the sick animais or the infected pastures. 
One C animal died a few davs after commencing the experi- 
ment without manifesting anv svmptom of the disease; the other 
remained unaffected. Ail four animais in A and B developed a 
typical attack of Gastro-enteritis. On the iSth, Tgth., 20th and 
24th dav after exposure the température rose to the neighbour- 
hood of**'T07° F. (41 °6 C.), and remained elevated for about ten 
days. Towards the end of the febrile reaction the animais mani- 
fested ail symptoma of the disease-lachrvmation and nasal dis¬ 
charge, stomatiti'S and diarrhoea, and three showed skin lésions. 
Coccidia were recovered in each animal during life, ancl in the 
