— 29? 
two which cliecl inarked changes had occurred in the mucosa of 
the large intestine (i). 
Guillebeau and Hess, and Zschokke, hâve described a Coc- 
cidiosis of cattle occurring at certain seasons in some cantons of 
Switzerland. These aiithors do not emphasise the presence of 
lachrymation and nasîd discharge, which are practicallv constant 
in East Africa, nor do thev draw particidar attention to the chan¬ 
ges in the ahomasiim and small intestine, which are frequent in 
some onthreaks here. Further they sav diagnosis is easy owing 
to the large number of oocvsts expelled in the faeces. In by far 
the majority of my examinations only merozoites hâve been en- 
countered in the faeces and on autopsy. Oocvsts hâve been seen 
in chronically affected animais and in some of those cases which 
had recently recovered. It is perhaps owing to the frequent occur¬ 
rence of a form undescribed in the ordinar\" text-books that the 
nature of this disease escaped observation for so long. 
In the dysenterie excreta of an acutelv sick animal, and in the 
scraping -of the inflamed rectum on autopsv, merozoites, either 
free or arrangée! like the quarters of an orange within the épithél¬ 
ial cells, are seen in variable numbers. Usuallv thev are very num- 
erous, up'wards of a hundred to a field being often présent in 
a fresh coverglass préparation mounted in saline solution. When 
examined in this manner the merozoites appear as comma-shaped 
bodies of a pale straw colour, capable of flexion and extension, 
but of verv limited progression. Tn the fresh State thev measure 
about II y to iq y in length (some, however, appear as short as 
6 y or 8 y), and from 1,5 y to 2,5 y at the widest part, which 
lies at about 33 % of the length, the upper third is rounded at the 
extremitv and the lower two-thirds taper to a hlunt point. There 
appear two types of merozoites, the one longer and finer than 
the other the significance of this has not vet heen ascertained 
here, but thev mav represent earlv sexual dimorphism. 
The oocvsts range from 14 y to 20 y in length, by 12 y to 
18 y in breadth (average 17 y by 15 y): they are clear and trans¬ 
parent with a definite contour and finely granular protoplasmic 
contents frequentlv aggregated towards the pôle opposite to the 
micropyle. 
(i) Some further details of these experiments appear in a short paper for 
ag'riculturalists in the A g ri cuit lirai Journal of Easi Africa, Vol. TI, Part. I\', 
January, 1910, 
