— 383 — 
"l'he splenic piilp is not increased in amount in mules but there 
is a quantity of bloocl pigment in irregular clumps lying free in 
the splenic spaces. 
In one mule in the fourth week the following blood picture was 
seen : 
R. B. C. 2.500.000 
Leucocytes . 12.500 
Polymorphonuclears . 26 % 
Large and small mononuclears . 73 % 
Myélocytes . 1 % 
100 % 
In most animais there is an eosinophilia due to intestinal para¬ 
sites (nematodes). 
Trypanosomes are found in ail tlie animais presenting the signs 
and lésions outlined above. The trypanosome appears and dis- 
appears with irregularity, appearing in numbers of from one to a 
film to six or ten to a field for a day or two, then disappear- 
ing for six or seven days to re-appear again during a febrile par- 
oxysm. The trypanosome is not as long as T. le’ivisi and its acti¬ 
vité \ aries ; — sometimes its motion is very rapid, at other times, 
verv slow and jerkv. The undulating membrane is well develop- 
ed, while the free flagellum is short. The trypanosome does not 
cause the commotion among the red blood corpuscles that T. 
leivisi does, probably on account of the shorter length of the for¬ 
mer. 
In stained préparations from different sources: horse, mule 
and guinea pig, its length varies from 12 to 28 p, its breadth 2 to 
4 p. Most specimens are 16 to 18 p in length. The trophonu- 
cleus is a little posterior to the centre i :2.8-i :2.4 The kinetonu- 
cleus is placed ciuite posteriorly and is of fair size about o p 5 
in diameter. The posterior end is often blunt and although some 
préparations contain many acutely pointed specimens it is never 
attenuated to the degree that the posterior end of T. Icii.'îsi is. 
There appear to be at least two types, —• a relative!v long form 
and a commoner stumpv one: 
Dimensions of 
Longer form Shorter form 
Length . 28 p 16 to 18 -a 
(a few 12 to 14 p) 
Breadth . ....... 2 u 2 to 4 u 
(some 3 to 4 u) 
Distance from 'uinetonucleus to poste¬ 
rior tip .. 1,75 p at tip 
Distance from posterior tip to middle 
of trophonucleus 
10 u 
7.5 p 
