- 633 — 
Morphology of parasites. — For the most part the parasites con- 
form to the typical Leishmania tropica, but will probably require 
spécial and detailed description. Practically ail the forms which 
hâve been described in oriental sore are présent, but careful exa¬ 
mination will be necessarv in case différences, either in struc¬ 
ture or arrangement, exist. 
At présent we need only mention the curved blepharoplasts 
which struck us as peculiar and the bodies staining a rose-pink. 
Examination of sections stained with eosin and haematoxylin 
showed those latter to be plasma cells. 
The spécial form of large cocci found in the growths contai- 
ning no Leishmania and in the cheesy matter from the neck tu- 
mour also claim attention. They are 4 to 6 times the size of the 
small cocci présent and tend to stain very feebly at their centres. 
Indeed some of them présent centrally placed unstained areas. 
They may occur in clumps or in pairs and then may ressemble 
in some measure huge gonococci. It is not likely that they are 
concerned with the Leishmania infection save in the way of svm- 
biosis. Carter 2 bas pointed out that L. tropica grows best in 
culture, when associated with masses of cocci and bacteria. 
Although the suggestion as regards the origin of the blue, 
homogenous masses may be correct, it is curious that many of 
them are very régulai* inoutline, spherical or oval and resembling, 
as one may say, for want of a better term « washed out » lympho¬ 
cytes, whose nuclei hâve vanished. 
The white cheesy matter is no doubt sebaceous in origin. 
Histo-pathology of growths. — The first growth excised was 
a small one, accessory to that on the left forearm, subsequently 
removed. 
The tissue was fixed in formol alcohol, hardened in alcohol, 
cleared in xylol, imbedded in paraffin and after the usual treat- 
ment stained in a variety of ways. The earlier sections were sli- 
ghtly thick and at first glance exhibited ail the appearance of a 
squamous carcinoma of the skin. The most prominent feature is 
the presence of numerous, typical cell nests (fig. 5) which, ac- 
cording to Lazarus-Barlow 3 , may, for ail practical purposes, be 
taken as diagnostic of that condition. Leaving the clinical his- 
torv out of account, however, it was seen évident that we were 
not dealing with a malignant growth. There is an increase in the 
rete Malpighi, long branching columns of which stretch down 
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