cependant un élément utile de diagnostic. Il mériterait d’être re¬ 
tenu comme un des « petits signes » et un caractère d’identifica¬ 
tion de ces germes secondaires. 
Laboratoire de bactériologie de la Marine, Toulon. 
Plague treated with anti-pest sérum 
By TODD. 
Thirteen cases bubonic plague were treated with anti-pest sé¬ 
rum from the Pasteur Institute, ign. 
Case i. —■ Male, âge 22 years. Seen first April 22nd., at which 
time he showed great prostration, température 106.2, had some 
nausea and a bubo in left groin below Poupart’s ligament. There 
was no suppurating point on the limb below the bubo. Patient 
said the bubo and other symptoms began April 22nd. 50 cc. sé¬ 
rum was injected into the vein and 40 cc. subcutaneously. April 
23rd. patient was again seen, température was 104, felt better but 
refused another injection of sérum. April 24th. patient died. 
Case 2. — Girl. âge 9, was brought from a house said to hâve 
had a recent death from Plague. Bubo developed in groin night 
of May 4th. Morning of May 5th. when Patient was first seen, 
température 102.5, signs of prostration, pain in bubo with no 
sign of infection in limb below the bubo. 45 cc. sérum was in¬ 
jected intravenious and 40 cc. subcutaneous. Morning of May 
6th. patient again seen température 99.5. Pain in bubo hai dts- 
appeared and facial expression much improved. Patient was again 
seen on May 7th. and 8th. when the température was normal. 
Later report showed this case recovered. 
Case 3. — Female, âge 32, from same house as case 2. Night 
of May 5th. had chill. Morning of May 6th. at first consultation 
showed bubo in right groin below Poupart’s ligament, tempéra¬ 
ture 102.4 and some prostation. Injected 40 cc. intraveniously 
and 50 cc. subcutaneously. May 7th. température 99.6 and bubo 
still painful but patient feeling better. May 8th. température 99.5, 
bubo still painful, tho less than when first seen. Report from pa¬ 
tient several weeks showed that she recovered. 
Case 4. — Female, âge 38. At first consultation May 17th. tem- 
