Nov. 3,1923 Iron Content of Blood and Spleen in Equine Anemia 241 
from normal horses are in accord with those of other observers. It is 
of interest to note the enormous increase in iron in the spleens of old 
animals over that in young ones. A study of Table I indicates that the 
quantity of iron is greatly increased in the spleens of young horses suffering 
from acute infectious equine anemia, a condition which would naturally 
follow from the great destruction of red cells. Such a statement does 
not hold true, however, for old horses or chronic cases. The spleens 
from old animals with chronic anemia usually show less iron than those 
from old normal horses. The weight of the spleens from the acute 
cases is nearly five times as great as those from normal animals or ani¬ 
mals with chronic anemia. It is worthy of note that the old horses 
suffering from the disease in an acute form had greatly enlarged spleens, 
but the total iron content was only slightly greater than in the old 
animals that were normal. This is just contrary to the results found 
in No. 6. There seems to be no increase in iron in the spleens of young 
animals with chronic cases. As a general observation, the evidence of 
anemia is less marked in the chronic cases than in the acute ones. 
Table II .—Iron content of horses* blood in infectious equine anemia 
No. 
Condition of animal at time of taking, 
blood. 
Date. 
Solids, air- 
dry parts 
per i,ooo. 
FesOs in 
fresh parts 
per 1,000. 
Hemo¬ 
globin. 
Erythro¬ 
cytes. 
2 
2 
8 
8 
9 
12 
15 
18 
18 
18 
18 
20 
21 
21 
21 
21 
21 
22 
23 
23 
23 
24 
24 
24 
753 
753 
753 
753 
X 
DC 
Normal. 
-do. 
-do. 
-do. 
_do. 
Sick. 
Normal. 
_do. 
Sick. 
_do. 
Normal. 
Normal, bled 10 liters Aug. 8. 
Normal. 
_do. 
Sick. 
_do. 
_do. 
Normal, bled 9K liters Aug. 8. 
Normal. 
Sick. 
.do. 
Normal, 
.do. 
Sick... 
-do. 
Normal, 
-do. 
-do. 
Very ill 
Normal. 
Apr. 
May 
Apr. 
May 
May 
June 
Aug. 
Sept. 
Nov. 
Aug. 
June 
Aug. 
Sept. 
Sept. 
Sept. 
Aug. 
Aug. 
Sept. 
Nov. 
Sept. 
Nov. 
Nov. 
Apr. 
June 
Aug. 
Sept 
June 
June 
Averages: 
Normal 
Sick... 
Bled. . 
11 
27 
11 
26 
11 
29 
4 
26 
12 
1 
14 
9 
12 
12 
18 
30 
12 
26 
12 
1 
18 
1 
14 
11 
9 
12 
12 
19 
4 
196. o 
215.0 
200. o 
204. 6 
197-4 
211.1 
231.6 
251. 2 
193-7 
195-3 
230.7 
182. 4 
188.5 
200.1 
158.4 
I 53 - 4 
147-9 
149.8 
205.9 
178.8 
182. 5 
179.1 
181. 5 
227. 6 
146.7 
200. 7 
190. 2 
186. 1 
o- 59 
•63 
59 
55 
65 
45 
7 6 
86 
45 
53 
55 
5 i 
44 
Per cent. 
90 
7, 964,000 
IOO 
8,032,000 
90 
7, 244,000 
90 
7, 648,000 
90 
7,86 0,000 
6, 836,000 
90 
IOO 
7,964,000 
IOO 
7, 856,000 
80 
7, 288, 000 
80 
6,972,000 
90 
8, 262,000 
80 
6,974,000 
36 
30 
33 
35 
59 
36 
40 
42 
46 
53 
23 
59 
49 
50 
14 
63 
80 
6,464,000 
90 
70 
80 
90 
80 
7,844, 000 
6,864, 000 
6,824,000 
6, 988, 000 
6,464,000 
IOO 
7, 764, 000 
90 
30 
7, 688, 000 
3,486, 000 
204. 6 
173-9 
166. 1 
•577 
• 37 i 
•340 
91 7, 622, 000 
73 6,371,000 
60376—23 - 5 
