40 
The Bulletin 
To Mice.—Experiment 23 .—Opportunity has not been afforded in the 
present experimental study to secure conclusive data upon butter as an 
agency in the transmission of milksickness. Three mice were fed but¬ 
ter made from the milk of a cow feeding upon white snakeroot. One 
died about two weeks after feeding was begun, another a week later,, 
while the other one remained unaffected. Aside from general debility,, 
no other symptom was prominent in these two animals, and the cause of 
their death could not be determined with certainty. It is reasonable ta 
conclude, however, in the light of experiments on milk as a carrier of 
milksickness, that the disease may he transmitted through butter. 
No clear-cut evidence pointing to a relationship between cheese and 
the development of the disease appears in available medical literature. 
Some few writers (Scott, 1889) assume that it is a generally accepted 
fact and in view of the evidence that milk and butter are capable of 
transmitting the disease, it is logical to suppose that cheese may also 
be a carrier. No feeding tests, however, have ever been directed toward 
the settlement of this claim. 
b. Through the Agency of Meat 
Numerous records exist of the transmission of this disease through 
the eating of flesh of animals affected with trembles. Coleman (1822) r 
Lewis (1829), Sale (1891), and Conner (1904) cite specific instances 
of the acquisition, by man, of this disease from meat. Yandell (1867) 
has included in his account statements which are contrary to this idea. 
Statements apparently from eye-witnesses (Coleman, 1822; De Bruler, 
1858) have, moreover, been made to the effect that carnivorous animals 
may acquire the disease from the flesh of animals dead of trembles. 
More remarkable than this, however, is the statement that these ani¬ 
mals can transmit the disease to others indefinitely. Instances like the 
following from McCall’s (1830) report illustrate the point in question. 
Some sheep which died of trembles were eaten by hogs, which in turn, 
succumbed to the same disease. The carcasses of all of the hogs except 
one were burned. Chickens which ate of this one were eaten in turn by 
persons who subsequently developed cases of milksickness. Another sim¬ 
ilar record by De Bruler (1858) states that a cow gave the disease to 
her calf, whose body was eaten by dogs. The dogs in turn died of 
trembles and a pet crow which fed on the dogs’ flesh also died. 
The more recent experiments by Jordan and Harris (1909) in which 
four dogs were fed upon flesh of animals dead of trembles resulted in 
the production of no ill effects. 
To Dogs.—Experiment 2J +.—These results with meat are in accord 
with the results secured in the present studies. During 1916, the car- 
