The Bulletin 
41 
casses, including livers, hearts, kidneys, and spleens of three sheep dead 
of trembles were fed to three dogs with no resultant ill effects. During 
the next season, four dogs were given the bodies of eight animals with 
no manifestation of trembles. It can only he suggested with reference 
to the observations of others to the effect that carnivorous animals mav 
die after having eaten the flesh of an animal dead of trembles, that pto¬ 
maines may have been present as the result of bacterial growth. This 
was guarded against in the present experiments by placing the carcasses, 
immediately after the autopsies had been performed, in a refrigerator. 
Daily portions were then given sufficient to satisfy the dogs’ hunger. 
Summary of Deeding Experiments. 
During the course of the feeding experiments with white snakeroot, 
a total of 41 sheep and lambs have been subjected to experimental condi¬ 
tions. Three others died in the experimental work with sodium com¬ 
pounds, to be reported later in this paper. Twenty-eight of these died 
and all except two were observed to have been characteristically affected 
with trembles or milksickness. These two were infested with stomach 
worms, which infestation may have been a contributory cause of their 
death. Two lambs contracted milksickness from the milk of ewes feed¬ 
ing upon white snakeroot. 
Two hogs were fed white snakeroot. One of these animals contracted 
a fatal case of trembles and the other remained apparently unaffected. 
Twenty-nine guinea pigs, fifteen of which succumbed on the experi¬ 
ments, were given white snakeroot or some of the products prepared 
from this plant. 
Seven dogs ate of the flesh of sheep dead of trembles with manifestly 
no ill effects. 
Three mice were given butter from the milk of a cow feeding upon 
white snakeroot. Two of them died while the other remained unaffected. 
Post-Mortem Examinations 
ISTo detailed studies of the pathological anatomy of animals dead of 
trembles or milksickness, other than those of Jordan and Harris (1909) 
appear in the voluminous literature on this disease. These authors give 
a general historical account of autopsies by other writers. These ac¬ 
counts give the impression of being fragmentary and indicate a lack of 
familiarity with anatomy in general and of experience with making 
post-mortem examinations. Such statements as the following indicate 
the point in question. 
Bennett (1822) says that the stomach contents of cattle is dry and 
that the liver has a morbid appearance. Beck (1822) describes the 
heart and aorta as greatly enlarged and their inner coat sloughy. Mil- 
4—Bulletin 
