42 
The Bulletin 
ler (1867) asserts that gastric and hepatic lesions accompany the dis¬ 
ease. Idibberd (1844) mentions the finding of a diminution of the cal¬ 
iber of the stomach and intestine in all of the cases examined. Menden¬ 
hall (1861) describes the inner coat of the stomach and intestine as 
being gangrenous. Newman (1867) records the singular observation 
that “in examining a milk cow after death the skin was found very much 
thickened and covered with small pustules.” Dicky (1852) states that 
the peritoneum and small intestine showed signs of inflammation. 
Graff (1841) says that there is evidence of cerebral inflammation, of a 
similar condition of the stomach and small intestines, that the spleen 
is enlarged and the liver softened. Way (1893) noted congestion of 
the cerebral meninges in the case of a six-weeks-old calf. 
Jordan and Harris (1909) had opportunity to perform autopsies 
upon several cattle, two lambs, and one horse. The following account 
of the microscopical appearance of these animals covers their findings. 
Externally the body presents nothing on inspection that is worthy of 
note. There may be present in the pleural cavities a small quantity of 
clear, yellow fluid. On opening the thoracic cavity, the lungs do not 
collapse. A quantity of frothy fluid exudes from the sectioned surface 
of the lungs. As a rule, the pericardial sac contains varying quantities 
of clear, straw-colored fluid which coagulates when exposed to the air. 
Numerous ecchymotic areas which are more numerous at the base of 
the heart, occur along the course of the cardiac veins. There was noted 
on section of the heart either fatty areas or streaks, or cloudy swelling. 
The peritoneal cavity contains no abnormal amount of serous fluid. 
The liver is uniformly enlarged and of a purple color, being full of 
blood. The consistency of the liver substance is soft and friable, and 
of the “nutmeg” appearance. Blood drips freely from the sectioned 
surface. The parenchymatous tissue is fatty. The kidneys are always 
enlarged and engorged with blood. Cloudy swelling of the parenchyma 
and in some cases slight fatty changes are noted. The bladder may be 
injected. In some cases, the urine is cloudy and apparently contains 
blood. The mucosa of the small intestines may show injection and 
ecchymoses. The meningeal vessels of the brain appear congested. 
In the microscopical examination, these authors find that the most 
profound pathological changes occur in the heart, liver, and kidneys. 
In the heart there may be noted cloudy swelling and fatty changes. In 
the liver the parenchymatous cells appear swollen with more or less 
cloudy swelling and fatty metamorphoses. The central veins are dis¬ 
tended with blood. The kidneys show hyperemia, glomerulitis, and par¬ 
enchymatous degeneration. 
The following is a detailed report of seven representative cases in 
sheep and lambs. 
