1972 
Hydnocarpus eastanea, from the Martaban Hills, in lower Burma. 
"The seeds, packed in charcoal for the long journey, arrived in 
good condition, and were carefully raised in germinating flats, and then 
transplanted into individual pots and held for a year, when they were 
ready to be set out. The work of planting was done by the Board of 
Agriculture and Forestry with the cooperation of the Hawaiian Sugar 
Planters' Association. 
"On the advice of Mr. Rock, the well-drained foothills in the 
Waiahole Forest Reserve, on the windward side of the island of Oahu, 
over the mountain range from Honolulu, were selected as the site for 
the plantation of these trees, which in about eight years, it is hoped, 
will begin to bear the round fruit packed with seeds from which this 
much-desired oil is obtained. 
"The properties of chaulmoogra oil for the treatment of leprosy 
have been recognized from early Asiatic history, and particularly in 
India it has been used as a palliative. Taken by way of the mouth, its 
administration was frequently attended by amelioration of the disease, 
although this was nauseating and offensive to the stomach, and at best 
the action was slow. More became known about chaulmoogra oil in 1904, 
when Dr. F. B. Power, of the Bureau of Chemistry, United States Depart- 
ment of Agriculture, determined the true origin and nature of the oil 
and succeeded in separating the physiologically active acids. 
"In Hawaii, where the injection of chaulmoogra oil was tried at the 
Kalihi Leprosy Hospital by officers of the United States Public Health 
Service, the results led them to believe that a greater therapeutic 
value could be obtained from the oil if the active agent or agents were 
isolated and the liquids made more suitable for intra-muscular or intra- 
venous injections. 
"By a happy combination with the Territorial Board of Health and 
the United States Public Health Service, an excellent opportunity was 
afforded for the use of these derivatives in the Kalihi Hospital, near 
Honolulu, where the patients were under constant observation and con- 
trol. Cases which improve to the point where the clinical signs have 
disappeared and the bacillus can no longer be demonstrated are recom- 
mended for parole. There is no way of demonstrating that any person 
has been absolutely cured of leprosy, but the patients who are paroled 
are believed to be free from the disease. In the great majority of 
cases which become bacteriologically negative there has been no reap- 
pearance of the disease. During a period of fourteen months ended March 
15, 1924, 50 per cent of the leprosy patients at the Kalihi Hospital have 
recovered as a result of this specialized treatment and have been pa- 
roled. During the past five years over 260 patients have been discharged 
as cured. Only forty-five of these have returned on account of a recur- 
rence of the disease. 
"The oil now used for these derivatives is obtained from India, 
