Bayer 22408 (0,0-Diethyl O-naphthalimido phosphorothioate) 
32 
Pp “-labeled Bayer 22408 was applied dermally as a 0.5% emulsion to 
Holstein cows. The intact insecticide was found in the milk for 6 days. 
The oxygen analog was not found in milk but constituted the predominant 
non-hydrolyzed product in the feces (Buttram, 1964). 
fe) O 
Ge: ae: 
N-P-OEr) —> N- E 
. ‘Oo YN 
Oo 
Bayer 22408 Bayer 22408 "oxon" 
Bayer 25141 (0,0-Diethyl O-p-methylsulfinylphenyl phosphorothionate) 
Bayer 25141 underwent slow oxidation in air to form the sulfone 
0,0-diethyl O-p-methylsulfonylphenyl phosphorothionate. In addition to 
this, the characteristic isomerization of phosphorothionates to phosphoro- 
thiolates also occurred, 
Metabolism studies with roaches have indicated dheipiecene of the 
isomeride and sulfone of Bayer 25141 and the S-ethyl isomer of the 
sulfone (Benjamini et al., 1959a, b). 
31 
