Botran (2,6-Dichloro-4-nitroaniline) 
Botran was strongly fixed in clay soils and was not completely 
extracted from treated soils. It was slightly water soluble and 
leached only slowly (Groves, 1965). 
1-Bromochlordene 
Corn borers metabolize this compound to the corresponding epoxide 
(Murphy et al., 1965). 
Captan (N-Trichloromethylthio-4-cyclohexene-1,2-dicarboximide) 
The intercellular breakdown product of captan, thiophosgene, is 
capable of inhibiting certain enzyme systems that have iseatnaxyines as a 
coenzyme (Duggar et al., 1959; Horsfall and Rich, 1957; Kittleson, 1952; 
Lukens and Sisler, 1958). Captan reacted with sulfhydryl compounds, in 
general (Owens and Blaak, 1960; Sisler, 1963). Products of the reaction 
with cysteine were cystine, tetrahydrophthalimide, hydrogen sulfide, 
carbon disulfide, 2-thiazolidinethione-4 carboxylic acid, and HCl. The 
trichloromethylthio group and thiophosgene were apparently intermediates 
in the formation of 2-thiazolidine-4-carboxylic acid. Although captan 
did not appear capable of reacting with other than sulfhydryl groups, the 
trichloromethylthio group of thiophosgene released from captan by sulfhydryl 
groups was apparently capable of reacting with amino, hydroxyl, sulfhydryl, 
44 
