
p?*. labeled coral was applied dermally to a cow and a goat. Unex- 
tractable residues were significant in tissues of both animals. Hydrolysis 
products were below the limit of sensitivity of the method. Many tissues, 
particularly fat, contained considerable radioactivity that appeared to be 
the oxygen analog of coral. The peak blood level of radioactivity for the 
cow occurred at 6 days; for the goat, at 6 hours and then again at 5 days. 
Cow cholinesterase continued to drop for seven days but recovered by the 
end of two weeks (Kaplanis et al., 1959a; Krueger et al., 1959a; Robbins 
et al., 1959). 
Most of the radioactivity appearing in the urine was as hydrolysis 
products. Some of the oxygen derivative of coral was found in the initial 
(up to 6 hours) collections but thereafter hydrolysis products were pre- 
dominant: 35% phosphoric acid, 17% diethyl phosphoric acid, 29% diethyl 
phosphorothioic acid, and 18% as the de-ethylated coral or its oxygen 
analog. Fractionation of the feces gave coral and its oxygen analog, 
primarily. Results obtained from the study with the goat were similar to 
those of the cow (Kaplanis et al., 1959a; Krueger et al., 1959a; O’Brien 
and Wolfe, 1959; Radeleff and Claborn, 1960). 
When Rhode Island hens were fed mash containing labeled coral, consid- 
erable more radioactive material appeared in the yolk than in the white or 
shell of eggs. The peak of radioactivity in the eggs appeared 11 to 15 
days after the beginning of the treatment and was present as long as 6 
to 8 days after return to normal diets. The decline in tissue residues 
was not paralleled by an increase in egg residues. From feces both coral 
56 
