indicated that the complex was not a glucuronide but did suggest an amide 
linkage, such as in hippuric acid. 
A pathway for the metabolism of DDT in rats (Finley and Pilmore, 
1963; Datta et al., 1964; Klein et al., 1964; Peterson and Robison, 
1964) and yeast (Kallman, 1963) has been proposed on the basis of studies 
with DDT and related compounds. These studies indicated DDD as an 
intermediate. A phenolic compound was also implicated (Morello, 1965). 
Studies suggested that the major fecal products in rats consisted of DDA 
conjugated with cholanic acid or amino acids (Jensen et al., 1957). After 
administration of p,p'-DDT in oil and p,p'-DDA in water to rats via stomach 
tube, a conjugate of p,p'-DDA was isolated from feces and urine. This 
conjugate contained one molecule each of serine and aspartic acid together 
with 8 molecules of water of hydration per molecule p,p’-DDA. 
The presence of four other metabolites was also indicated, possibly 
identical with 
1) p,p'-dichlorobenzhydrol 
2) p,p'’-dichlorodiphenylmethane 
3) p,p'-dichlorobenzophenone 
4) DDE 
(Pinto et al., 1965). 
Other studies have indicated that DDD appears in those samples which 
are permitted to decompose some time after sacrifice and not in those 
samples analyzed immediately (Barker and Morrison, 1964). An isolate, 
Proteus vulgaris, from a mouse intestinal flora converted DDT to DDD 
74 
