Delnav (2,3-p-Dioxanedithiol S,S-bis[0,0-diethyl phosphorodithioate]) 
When applied dermally to cattle, delnav was absorbed into the blood 
rapidly and the peak level of radioactivity was reached in 3 hours; whereas, 
in orally treated animals, it occurred in 12 hours. Blood radioactivity 
persisted at least one week after application. The radioactivity pattern 
of the urine followed that of the blood (Chamberlain et al., 1960). 
Chromatography autoradiography showed that diethyl phosphoric, 
diethyl phosphorothioic, and diethyl phosphorodithioic acids were the 
major products of hydrolysis. Cis and trans delnav, dioxane derivative, 
and three unknown compounds were also found. A highly polar compound 
present at the origin point in the chromatography of the urine was presumed 
to be phosphoric acid, (Arthur and Casida, 1959). Analyses showed that 
technical delnav, with 76.3% as trans or cis, was present in the omental 
fat. 
fy HS-P-(0CpHs) 
ee Diethyl Phosphoro- 
dithioic acid 
Delnav 
S- B- (0C,Hs), g : 
—— 
om Diethyl Phosphoric Diethyl Phosphoro- 
i “(CC 2Hs5), Acid thioic Acid 
HPO, 
80 
