Endosulfan (Thiodan) 
When endosulfan was administered orally in corn oil to white rats, 
both isomers and the alcohol metabolite were identified by paper 
chromatography (Lindquist and Dahm, 1957; Terranova and Ware, 1963). 
After topical application of 
cl4 
-endosulfan to Musca domestica 
(Barnes, 1965; Barnes and Ware, 1965) or to leafy plants (Cassil and 
Drummond, 1965), endosulifan sulfate was isolated. 
metabolites were also found but not identified. 
Several additional 
Characteristics of the 
unidentified compounds indicated that they were probably conjugates of 
endosulfan as either the glucoside, the glucuronide, or the ethereal 
sulfate. 
C 
Cl 
rat 
Cl 
C CH»OH 
Cl 
CH, OH 
Endosulfan 
Alcohol 
Glucoside or Glucuronide 
CH» -0 
\ 
S=0 
/ 
1 CH, -0 
Endosulfan — fly 
Cl 
CH» -O 
Cl 
CH, -O 
Cl 
Endosulfan 
sulfate 
109 
Cl \ 
/ 
0 
~ 
5 
\ 
4 
0 
