Piperonyl Butoxide 
Exposure of Madeira roaches to cl4_1abeled piperonyl butoxide gave 
rise to several water soluble metabolites which were unidentified. Dis- 
tribution of radioactivity showed that the brain and thoracic ganglia, 
fore- and hind-gut, and Malpighian tubules of the kidney contained the 
greatest amounts of radioactivity per unit weight (Schmidt and Dahm, 1956). 
Prolan 
Sublethal doses of prolan were metabolized to unidentified products. 
In addition to unchanged prolan, an acidic metabolite, possibly bis-(p- 
chlorophenyl) pyruvic acid, has been isolated from the excreta of house- 
flies. U. V. and I. R. absorption and chemical tests show that the NO. 
group has been lost and that a >C=0 is present. It has been shown that 
this is not DDA (Perry and Buckner, 1959; Perry, 1960). 
Ect —>>- oe gp gape 
HC-NO, 0 
CH, Cc 
S ‘OH 
Prolan bis-(p-chlorophenyl) pyruvic acid 
138 
