Sesone (2,4-Dichlorophenoxyethylsul fate) 
At a pH of 3.0 - 4.0, the ethanol analog of 2,4-dichloroethylsulfate 
was formed by hydrolysis. Above pH 5.5, this reaction ceased unless 
microflora were present. In the presence of Bacillus Cereus var. Mycoides, 
activation proceeded via enzymatic hydrolysis and oxidation probably to 
2,4-dichlorophenoxyacetate (Carroll, 1951, 1952; Audus, 1952a; Vlitos, 
1952, 1953; Vlitos and King, 1953; Audus, 1953). 
0 
7 
~CH, ~CH, -0 -SO, -ONa CH, -CH,OH ~CH, “Cy 
OH 
C1 1 Cl 
See od — p>» 
1 l 
2,4-D 
Sesone Sesone 
Alcohol 
Sevin (1-Naphthyl-N-methylcarbamate) 
Feeding studies with cows indicated that sevin was hydrolyzed to 
l-naphthol and excreted in the urine only. In other studies with a goat, 
an unidentified metabolite was found in the milk (Whitefust et al., 1963). 
Labeled sevin was administered intraperitoneally in polyethylene 
glycol to guinea pigs and rats. Within 24 hours 85% of the administered 
count was recovered in the urine in both cases (Knaak et al., in press). 
When naphthyl labeled sevin was administered to the rat, exo, was 
not found. However, methyl and carbonyl labeled sevin gave rise after 4 
143 
