Toxaphene 
Very little information is available about the metabolism of 
toxaphene. Using bioassay methods, it was found that resistant flies 
could metabolize 4.0 mcg of toxaphene from an absorbed dose of 5.4 mcg. 
No metabolites were identified. 
Toxaphene is stored unchanged in fatty tissue of treated animals. 
Infrared shows presence of all absorption bands exhibited by toxaphene. 
Comparative bioassay and total chlorine showed that total organic chloride 
in fatty tissue has about same toxicity to flies as an equivalent amount 
of toxaphene (Diephus and Dunn, 1949). 
Triazines 
Chlorinated: Simazine, Atrazine, Propazine, Ipazine 
‘ 
Mercapto: Prometryne 
Since chlorosis is the first sign of the effect of triazines on 
plants, interference with co, assimilation and sugar formation can be 
expected, Studies showing that the Hill reaction is inhibited confirmed 
this. 
Simazine (2-Chloro-4,6-bis[ethylamino] -S-triazine) 
Work with labeled simazine has shown that a wide variety of 
plants, resistant and nonresistant, metabolize this material 
(Foy and Castelfranco, 1960; Foy, 1961c; Sheets, 1961). Using ring- 
160 
