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SUMMARY 
. Contrary to the usual experience that the uncomplicated ectopia of 
the pupil of the human eye is unilateral and non-hereditary, this ar- 
ticle is the first to show a pedigree in which 15 persons in 4 genera- 
tions possess the character bilateral. 
. This ectopia behaves as a dominant unitcharacter, without sex- 
preference. 
. The direction of the ectopia is the same with all members of the fa- 
mily, namely, upward-inward (idiotypic). 
. As to the paratypic (fluctuating) variability we see different gra- 
duations, from scarcely abnormal to the highest degrees. Most ca- 
ses were correlated with narrowness of the pupil, structural chan- 
ges in the iris, strong rests of membrana pupillaris and the absence 
of a limbus. In only one case there was a very slight microcornea 
plana on both eyes and a slight coloboma of the lens on one eye 
with pigmentation of the membrana capsulopupillaris. 
. The character is independent of the colour of the iris and of refrac- 
tion anomalies. 
. Contrary to what has been the outcome of the majority of the ca- 
ses, hitherto published, about the dominant hereditary character 
of the uncomplicated ectopia of the lens, it was recessive in the 
threee families in which the author met with the character. 
. To all probability the aetiology of these cases of ectopia of the lens 
must lie in the germplasm because the first family shows consan- 
guinity, the second racecrossing of the parents and in the third fa- 
mily a brother and sister both show the phenomenon. 
. In accordance with the result of the study of the literature that the 
combination of the ectopia pupillae et lentis bears a recessive cha- 
racter, the author publishes a case, whose germinal aetiology has 
been made probable by the occurrence of a case of unilateral mi- 
crophthalmia is the same family. 

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