Bayer 73 (Ethanolamine salt of N-(2-chloro-—4-nit ropheny1)-5-chloro- 
salicylamide) 
Following oral administration of labeled Bayer 73 to rats, there 
was still 55% of activity present after one hour and 10% after five hours. 
About 33% of the applied activity: appeared in the urine and 67% in the 
feces. Within 24 hours after administration, storage in tissues of rats 
was less than 1 ppm. Only 12% was detected in the urine of humans that 
ingested the material. 
Unchanged active ingredient was excreted in the urine of rats in 
very small amounts as a conjugate. The main metabolite, N-(2-chloro- 
4-aminobenzene)-5—chloro-salicylamide, was also excreted in the urine 
in a conjugated form (388). 
N05 — > Conjugate 

‘NH, ——> Conjugate 
48 
