

Application of aldrin to the American cockroach resulted in partial 
conversion to dieldrin (547). Similarly, tests with locusts (292) house- 
flies and mosquito (Aedes Aegypti) larvae (152, 829, 831, 536, 1155, 1428) 
showed that labeled aldrin was converted to dieldrin and hydrophylic com- 
pounds. In Musca vicina, studies demonstrated that the microsomes con- 
tained a system that was capable of causing this conversion and required 
NADPH and 05 (1197). The sulfur and bromine analogs of dieldrin (§35 and 
Br82 labeled, respectively), also were shown to be partly metabolized to 
water-soluble and insoluble compounds (1514). With nerve components, 
studies have shown that dieldrin forms a complex that is inextractable with 
organic solvents (939). Culex pipiens quinquelfasciatus mosquitoes metabo- 
lized dieldrin to a compound believed to be the aldrin glycol (diol) (1113, 
1625). 
Housefly and pig liver microsomes hydroxylated dihydroaldrin, in 
the presence of NADPH, to a mixture of exo- and endo-6-hydroxydihydro- 
aldrin (188, 1775). 
The conversion of aldrin to dieldrin has been found to occur in 
soil, (138, 521, 523, 786, 829, 869, 870, 1500) in general. In 1956 it 
was found that carrots grown in aldrin-treated beds contained dieldrin 
(548). Similarly, peanuts grown in an aldrin-treated bed contained dieldrin 
residues in the hulls, meat, and vine forage (97). Aldrin was also converted 
to dieldrin in mushroom compost (1592), radishes and other plants (1783). 
Ninety-two pure cultures were screened for aldrin-degrading activity. 
Most showed some capacity for converting aldrin to dieldrin. Of considerable 
interest was the ability of some fungi, actinomycetes, and bacteria to 
degrade dieldrin: trichoderms sp., fusarium, aspergillus, streptomyces, 
micromonospora, bacillus, nocardia and thermoactinomyces (1428). 
In studies designed to discover microorganisms that could degrade 
dieldrin, ten such microbial cultures were obtained. Two were identified 
to species level as Trichoderma viride; six were found to belong to the 
genus Pseudomonas; and two, to the genus Bacillus. Using radioautography 
and thin-layer chromatography, in addition to dieldrin, nine compounds 
were indicated. One spot matched authentic 6,7-transdihydroxydihydro- 
aldrin. The other spots were unidentified (936, 1599). In other studies, 
incubation with a pseudomonas sp. gave rise to nine compounds. Five of 
these were indicated: IV, XIII, XIV, XV, XVI (1684). Pseudomona 
melophthora degraded dieldrin, but no metabolites were identified (145). 
Trichoderma viride converted dieldrin into four metabolites, one of which 
was identified as 6,7-transdihydroxydihydroaldrin (1622). 
Aldrin was sprayed on apple trees in June and the rate of loss was 
observed. Twenty-four percent remained after one week and 2% after seven 
weeks, After eleven weeks, the residue consisted almost entirely of 
dieldrin and its UV irradiation products. By applying dieldrin at high 
rates, four conversion products were detected. Three of these were identical 
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