LT 

Pathway 
l. Oxidation 
(a) Hydroxylation 
(b) Side chain oxidation 
(c) Ether cleavage 
Cl- 
(d) Sulfoxide formation 
(e) N-oxide formation 
Table I 
Some Metabolic Reactions Common 
to Pesticides 
Schematic 
1 H 
O 
e 
Cl 0-CHy-¢-OH —— de C1 O-CH, -C-OH 
i e 
Hp] 
c ¢ 
Cl a 
Cl 3 Cl 
Q 
o-cH,-C-OH —z C1 OH 
0 
R-S-CH., > r-$-cu, 
0 
-(CH4) ~ (CH) 
st chee ame ae 
R-0 
‘“ 
N-(CH) NN=(CH3) 2 
2 
+ 
3 
Pesticide which 
undergoes this 
reaction 
2 ,4-D 
DDT 
2,4-D 
Phorate 
Schraden 
