Investigations have shown that DDT may be metabolized by insects to 
as many as 7 metabolites (unidentified) in addition to DDE, most of which 
are more polar than DDT (695, 878). 
The housefly, Musca domestica L., converted DDT to DDE and unidenti- 
fied water soluble products possibly conjugated with a carbohydrate (1147, 
1265, 1396, 1518). Fly homogenates, in the presence of NADPH,, converted 
DDT to kelthane (1427). 
American, Periplaneta americana L., and German, Blatella germanica 
L., cockroaches oxidized DDT to DDE and other water soluble products which, 
upon acid hydrolysis, could be extracted by ether (288, 693, 1217, 1518). 
It was thought that the water soluble material was a conjugate composed 
of a DDT metabolite and a carbohydrate (215, 1448). In the American 
cockroach, dichlorobenzophenone and what was believed to be dichloro- 
benzhydrol also were detected in the feces (1518). From the German 
cockroach, an enzyme system was prepared that oxidized DDT to a compound 
with the same chromatographic characteristics as dicofol (5, 527). 
Dichlorobenzophenone was also found in tissues after exposure of German 
cockroaches to DDD (527). Other studies indicated that various nerve 
components of both American and German cockroaches formed a complex with 
DDT (635, 942). 
Fifth-instar larvae of Aglais urticae (L.) (Lepidoptera: Nymphalidae) 
and fourth-instar larvae of Chorthippus brunneus (Thunberg) (Saltatoria: 
Acrididae) metabolized DDT to DDE (1747). 
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