Dicapthon (Dicaptan, Isomeric Chlorothion) [0-(2-chloro-4-nitropheny1) 
0,0-dimethyl phosphorothioate ] 
Rabbit and rat liver microsomes and housefly microsomes plus NADPH» 
and 05 were incubated with dicapthon In each case, the corresponding 
phenol was found. Activation of dicapthon to the corresponding oxon analog 
was observed. Some conversion of the oxon analog to the corresponding 
phenol was also observed (1700). 
Ditholane (EI-43064; Cyolane) [2-(diethoxyphosphinothioylimino)-1, 3- 
dithiolane ] 
No metabolites were identified or demonstrated. Differential 
cholinesterase inhibition was cited as evidence of degradation to the oxon 
analog (1739). 
149 
