Endothal [Disodium 3,6-endoxohexahydrophthalate] 
When labeled endothal was fed to adult rats (Wistar strain), over 902 
of the radioactivity was recovered in the feces as unchanged endothal. The 
remainder of the label was recovered unchanged in the urine and as expired 
C09 (1337). 
Radioactive tracer studies show that most of the endothal degradation 
occurred in the moist soil within 7-10 days and that the clto, produced is 
then taken up by the plant and incorporated into plant metabolites (492,1031). 
Labeled studies indicated at least two unidentified metabolites which were 
further metabolized. Indications were that the metabolites were organic 
acids and probably combined with amino acids (1027). 
Endothion [2-(S-Dimethylphosphorodithiomethy1)-5-methoxy-4-pyrone ] 
Endothion was applied to several species of insects and the degree 
of penetration and metabolism was studied. Three metabolites were isolated 
but the quantities were insufficient to permit rigorous identification (1419). 
After treatment of plants with S3°-endothion, the monomethyl 
derivative was detected (625). 
200 
