Famphur [0-(p-N,N-dimethylsulfamoylphenyl) 0,0-dimethyl phosphorothioate] 
Famphur was degraded at varying rates by mice, American cockroach 
(Periplaneta americana L.), and milkweed bugs [Oncopeltus fasciatus (Dall.)]. 
H*-labeled famphur was injected and analyses were made by thin-layer chroma- 
tography. In addition to famphur, both famoxon and N-desmethyl famphur were 
found (1095), 
Two white-faced western ewes and one heifer calf were treated with 
tritiated famphur. In addition to the oxygen analog, O0-desmethyl, 0,N- 
bisdesmethyl, two glucuronides, p-hydroxybenzenesulfonic acid, and several 
unknown metabolites were observed. The latter may be the mono- or di- 
dimethylsulfamoylphenyl sulfates. In rats, the major metabolites was di- 
methylsulfamoylphenyl glucuronide. 0,N-bisdesmethyl famphur, methyl- 
sulfamoylphenyl glucuronide, and p-hydroxybenzene sulfonic acid were also 
observed (528). 
