Telodrin [1,3,4,5,6,7,8,8-Octachloro-3a,4,7,7a-tetrahydro-4, 7- 
| methanophthalan] 
The secretion of telodrin or its metabolites was studied in cows 
by means of G. L. C. - electron capture. Residues of telodrin were found 
in the milk and meat of the cows in proportion to the level fed (118). 
Mosquito larvae were exposed to c-14_1abeled telodrin and four 
metabolites were obtained. Using paper chromatography, it was found that 
chlorine in the 1 and 3 positions was split off and the compound was identi- 
fied as a lactone (830, 831). 
When the metabolism of telodrin by microorganisms was studied, it 
was found that the molds, Aspergillus niger and flavus and Pencillum 
chryssogenum and notatum, could degrade telodrin. A hydrophyllic metab- 
olite was isolated but not identified. This appeared to be the same as 
one of the metabolites obtained when mosquito larvae were exposed to 
telodrin (831). 
cll, 0H C1 CH) 0H 
C1 
7 O 
CH,OH Y C7 
1 Non 

Cl 1 
Telodrin cr 

‘ it 

Lactone 
295 
