2,4,59,6-Tetrachloroisophthalonitrile (TCIN, Daconil) 
When yeast cells were exposed to TCIN, the derivatives formed 
resembled those formed by the reaction of glutathione with TCIN in vitro. 
Coenzyme A and 2-mercaptoethanol also readily formed derivatives with TCIN 
in vitro. The nature of these derivatives was studied using 2-mercapto- 
ethanol. Infrared spectra and chromatography of the four derivatives 
obtained indicated that one to four of the halogens had been substituted by 
2-mercaptoethanol (1745). 
No residues of daconil were found in millk of dairy cows fed this 
compound nor was intact daconil found in the manure or urine. Daconil 
rapidly decomposed in fresh rumen contents with production of two 
unidentified metabolites (586). 
Tetramine [Tetramethylenedisulfotetramine ] 
Uniformly, cl4_jabeled tetramine was administered to Pseudotsuga 
menziesii, Dactylis glomerata and Rubus ursinus. Tetramine moved upward 
in the xylem, but once deposited in tissue, became immobile. Slow de- 
gradation occurred in shoot tissue. Some eo, evolved (1185). 
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