2-Methoxy-4-sec~butylamino-6-ethylamino-s-triazine (GS-14 254) 
After a cow was given the methoxy-labeled triazine, about 15% of the 
label was expired. When ring-labeled material was administered, /6% of 
the dose was found in the urine and 10% in the feces after 120 hours. 
When methoxy-labeled triazine was administered to a goat, 83% of the 
dose appeared in the urine after 48 hours and 3% in the expired air after 
24 hours. Urinary metabolites were the same in both animals. Sixteen 
metabolites were observed in urine and feces. Those identified were: 
6-amino-4-sec-butylamino-2-methoxy- ; 4,6-diamino-2-methoxy- ; 6-amino-4- 
(1-hydroxy-sec-butylamino)-2-methoxy- ; 6-amino-4-(4-hydroxy-sec-butylamino) - 
2-methoxy- ; and 6-amino-4-sec-butylamino-2-hydroxy-s~triazines (1756). 
ha 
C7 i Ko -CH, 
ye 
GS-14254 
OCH, OCH, OCH, 
oO on 
aN 2 ae tke rel sei 
Hy-CH 0H Ho-CH3 
f 
OCH, OH 
o : an 
ely, Fas m oy, ye 
,~ 
HOCH, cH” i 
-CH, H5-CH3 
Ho 
316 
