Linuron (Afalon) [N-(2,4-dichloropheny1-N'-methy1l-N'-methoxyurea] 
Linuron in oil was fed to albino rats. Urine was collected and 
analyzed for metabolites (N-(3,4-dichlorophenyl)urea, N-(3,4-dichloro- 
phenyl)-N'-methylurea and 3,4-dichloroaniline were found free. M2- 
hy droxy-4,5-dichlorophenyl)-N'-methylurea, N-(5-hydroxy-3,4-dichloropheny1) 
urea and 6-acetamido-2,3-dichlorophenol were present as glucuronides or 
sulfates. Found bound and free were 2-amino-4,5-dichlorophenol, 2-acetamido- 
4,5-dichlorophenol, N-(2-hydroxy-4,5-dichlorophenyl)urea and N-(2-hydroxy- 
3,4-dichlorophenyl)urea (134). 
Linuron was also degraded by plants giving the 3,4-dichloroaniline, 
and CO» (1549). 
Monolinuron (Aresin) [N-(4-chlorophenyl)-N'-methy1l-N-methoxyurea] 
When aresin was fed to albino rats, the following metabolites were 
found both free and bound as glucuronides or sulfates: N-(2-hydroxy-4- 
chlorophenyl)-N“methylurea, N-(3-hydroxy-4-chlorophenyl)-urea; traces of 
N-(4-chlorophenyl)-N'~methoxyurea, 2-amino-5-chlorophenol, 2-acetamino-5- 
chlorophenol, N,N'-bis-(4-chlorophenyl)urea, 2-acetamino-6-chlorophenol, 
and N-(2-hydroxy-4-chlorophenyl)-N'-methy1l-N'-methoxyurea. N-(4-chloro- 
phenyl)urea and a trace of 4-chloroaniline were found free only. N- 
(2-hydroxy-4-chlorophenyl)-N'-methylurea was found in the bound state 
only (417). 
In plants, monolinuron was degraded to 4-chloroaniline and CO») 
(1549). 
340 
