YAWS AND SYPHILIS 305 
cells is different in tuberculosis and syphilis, so it is not impossible that there 
is a difference in syphilis and framboesia with regard to the manner of arrange- 
ment of the plasma cells. He believes that in framboesia one may find rings 
or zones of cells which consist only of plasma cells, and that these are found 
directly around the vessels of the papillary bodies, such vessels being delicately 
broadened or entirely unchanged. This infiltration is also observed about the 
wre 
+ 

No. 231. — Case 217. Photomicrograph illustrating infiltration of corium and papillae, 
and downgrowth of epithelium with abscesses in the stratum mucosum 
network of vessels of the subpapillary layer. These layers of plasma cells lie, 
however, more commonly below the papillae, particularly at the point of branch- 
ing of the vessel that leads to the papillae. These cells are often so numerous 
that the papilla appears to be completely lined with them. In his study of 
framboesia he has found such a condition common and, as he has never ob- 
served it in syphilis, he thinks it is worthy of some attention, although he does 
not wish to give it a pathognomonic role. He believes that the only character 
that is reliable and that can be used for diagnosis which is peculiar to syphilis, and 
occurs in all stages in similar typical form, is the classic modification of the 
