HORMODENDRUM INFECTION 343 

No. 267. — Case 500, camera lucida drawing illustrating cellular infiltration in the papilla 
and extending into the stratum granulosum and stratum lucidum. Zeiss objective AA, compen- 
sating ocular 10x 
blood vessels in the papillary layer occasionally round or budding spores of the 
fungi may be distinguished. In a very few areas small abscesses are found in 
the superficial portions of the stratum mucosum, over which the stratum corneum 
is greatly thinned and in which the nuclei still persist in the corneal cells. Finally, 
in some places the stratum corneum and stratum mucosum have been entirely 
destroyed for a short distance and the corium thus exposed. In such areas 
coagulation necrosis of the tissue has taken place and spirochaetes and fusiform 
bacilli have secondarily invaded the upper layers. Such a condition, however, 
is observed in only two places of the sections from one block of the tissue removed. 
In the other blocks of tissue the epithelium is more or less preserved. In all of 
the sections the corium is generally oedematous. There are many elastic fibers 
present, and newly-formed blood vessels are numerous. In the corium also one 
finds many miliary areas of infiltration with leucocytes and round cells. Prolif- 
