044 REPORT OF THE HARVARD AFRICAN EXPEDITION 








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No. 268. — Case 500, camera lucida drawing illustrating inflammatory reaction in the corium, par- 
ticularly about blood vessels and sweat glands. Zeiss objective AA, compensating ocular 6 
erating fibroblasts are also seen in the surrounding tissue. The infiltration 
occurs particularly about the sweat glands and blood vessels (No. 268). In 
other areas in the corium there are small haemorrhages about which a few 
round or budding spores of the fungus are visible. In still other small areas 
deep in the corium necrosis of the tissue has occurred, and in the vicinity there 
is marked infiltration with leucocytes, and occasional spores of the fungus may 
also be distinguished. 
At the time of removal of the tissues for histological examination, a tube of 
Sabourraud’s medium and one of agar were inoculated with serous fluid expressed 
from the cut surface of the lesion. These were the only culture tubes at hand 
on the one occasion that we had opportunity to observe the patient. An ex- 
amination of these tubes 36 hours later, after we had returned to the improvised 
laboratory on our boat, showed the surface of the agar tube entirely overgrown 
