1802.]  Feport of the Committee on Dr. Fenner’s Petition. 
ral way, and was attended by Mr. Ro- 
bert Pope, furgeon, from Staines, who 
pronounced the girl to be in a very dan- 
gerous fituation; having in the houfe at 
that time three perfons who had been 
inoculated with the cow-pox, the child 
above-mentioned, a maid-{fervant, and a 
little girl, and being defirous of proving 
the efficacy of vaccine inoculation, he fent 
for Dr. Jenner and permitted him to 
inoculate the child and one of the girls 
with variolous matter, taken from the 
‘maid-fervant; the fmall-pox took no 
manner of eff<& on either of them (the 
girl had been inoculated with vaccine 
matter four years before) the other girl 
that was not inoculated attended on the® 
maid-fervant the whole time until her 
death, and refifted the infection.—The 
efluvia in that part of the houfe was fo 
offenfive, that alt the fervants were 
obliged to be removed to another part of 
the houfe. Lord) Berkeley further ftated, 
‘That there is an old fervant now in his 
family, feventy-two years of age, who 
had the cow-pox, from milking cows, 
when a boy of fifteen, who has never 
been in the leaft cautious in guarding 
againft the finall-pox, but has expoled 
himfelf repeatedly, without being fenfible 
of its effeéts; and Lord Berkeley once faw 
him, himfelf, fitting next a boy who had 
the fmall-pox vifibly out upon him. (No.6.) 
Robert Pope, furgeon, at Staines, at- 
tended the maid-fervant from whom Earl 
Berkeley’s fon and the girl were inocu- 
lated with variolous matter; he depofed 
to the virulence of the difeafe, and to her 
death tn’ confequence. His opinion was 
not favourable to vaccine-inoculation on 
the firft publication of it; but he is fince 
pretty well convinced, that if properly 
conduéted, it is a preventive of fmall- 
pox, and he-has pradtiled it hfmfelf with 
fuccefs. (No. 7.) 
The Rev. G. C. Jenner is converfant 
in the praGtice of the vaccine-inoculation, 
and has inoculated three thoufand perfons, 
without meeting with one unfavourable 
cafe, although he has inoculated perfons 
ftom the earlieft infancy to eighty years 
of age, and under thofe circuniftances in 
which it would not be prudent or indeed 
fafe to inoculate with variolous virus, 
fuch as children at the time of dentition, 
and women in every ftage of pregnancy, 
from the firft month to the laft weck. 
Upwards of two hundred of his p2tients 
have fince been inoculated with a@ive 
fmal!-pox matter, and at leaft an equal 
number expofed to contagious effluvia, 
but in no one inftance was the fmall-pox 
preduccd. On the arms of fome of thofe 
| Montuty Maa, No, go, 
1? 
inoculated with fmall-psx, a flight local 
inflammation fhewed ittelf, which difap- 
peared in four or five days; fome of thefe 
perfons were put to the teit of the fmall- 
pox, after a period of a year. The per- 
fect puftule is always to be diftinguifned 
from the imperfect or fpurious, by thofe 
who have paid a proper attention to the 
practice of vaccine-inoculation. He be- 
lieves that vaccine inoculation will fre- 
quently fuperfede the infection of the 
fmall pox, when the patient has been ex- 
pofed to a variolated atmofphere previous 
to the inoculation, in confirmation of 
which he related a cafe under his own 
immediate obfervation. A boy, infected 
with the natural fmall-pox, came home to 
his father’s cottage; four days after the 
eruption had appeared upon this boy, the 
family (none of whom had ever had the 
fmall-pox) confilting of the father, mo- 
ther, and five children, were inoculated 
with vaccine virus; on the arm of the 
mother it failed to produce the leaft effect, 
and fhe had the fmall-pox; but the fix 
others had the cow-pox in the ufual mild 
way, and were not affected with the fmall- 
pox, although they were in the fame 
room, and the children flept in the fame 
bed with their brother, who was confined 
to it with the natural {mall-pox, and fub- 
fequently they flept with their mother. 
He is of opinion, that if the pra€tice of 
vaccine-inoculation is univerfaliy adopted, 
it will in a fhort time annihilate the {mall- 
pox. He has known many inftances of 
the infetion not taking in the early part 
of his prattice, owing to his ufine vac- 
cine-virus taken at too advanced a ftage 
of the difeafe; but fince he has made it a 
rule never to inoculate with matter after - 
the eighth or ninth day of the difeafe, he 
has feldom met with a failure; he inocu- 
lated two hundred and thirty-eight indi- 
viduals on the fame day, with recent fluid- 
virus, taken on the eighth day of the. 
difeafe, and every one of them had the 
cow-pox in the moft perfe@ manner. The 
progrefs of the cow-pox is in general uni- 
form; he has feen a few exceptions, one 
or two cafes have occurred when the pro- 
grefs of the difeafe has been retarded’ for’ 
at leaft a fortnight before there were any 
vifible appearances of the inoculation’ 
baving fucceeded ; the courfe of the fpu- 
rious diforder is univerfally quicker than 
the perfeét, fo as to form a certain ‘cri- 
terion between the forts in every cafe 
which has. come under his obfervation ; 
when*the puflule affumes the genuine’ 
character, the patiént may be confidered 
as fafe- from any future attack of the 
_finall-pox, ahhough there has been no . 
C apparent 
