63) Literary and Philofophical Intelligence. 
fier, and when the inoculator did not after- 
wards fee the patients, and therefore could 
Net afcertain whether infe€tion had taken 
place or not; and that to this caute are cer- 
tainly to be attributed many of the cafes ad- 
duced in proof of the inefficacy of cow-pox. 
VILE. «© That fome cafes haye been brought 
Before the Committee, on which they 
ééuld form nodecifive opinion, from the want 
of neceflary information as to the regularity of 
the preceding -vaccination, or the reality of 
the fubfequent appearance of the fmall-pox. 
IX. 6¢ That it is admitted by the Commit- 
fee, that a few cafes have been brought be- 
fore them, of perfons having the fmall-pox, 
who had apparently paffed through the cow- 
pox ina regular way. ak 
X. <¢ That cafes, fupported by evidence 
equally ftrong, have been alio brought before 
them, of perfons who, after having once re- 
gularly pa‘led throagh the {mall-pox, either 
by inoculation or natural infe@tion, have had 
that difeafe a fecond’ time. 
ML *¢ That in many cafes, in which the 
fmall-pox has occurred a fecond time, after 
inoculation or the natural difeafe, fuch re- 
€urrence Aas been particularly fevere, and of- 
ten fatal; whereas, when it has appeared 
after vaccination, the difeafe has generally 
beep fo mild, as to lofe fome of its charac- 
teriitic marks, and in many inftances to ren- 
der its exiftence doubtiul. 
XIE. ‘* That it is a faét well afcertained, 
that in fome particular fates of certain con- 
ftitutions, whether vaccine or variolous mat- 
ter be employed, a local difeafe only will be 
excited by inoculation, the conftitution re- 
maining unafiected; yet that matter taken 
fiom fuch bocal vaccine or variolous puttule 
is capable of producing a general and perfect 
diicaie. 
MIL. ** That if a.perfon, bearing the 
ftronge‘t and mo‘t indubitable marks of hav- 
inz had the {mali-pox, be repeatedly inocu- 
hated for that difeate, a puftule may be pro- 
duced, the matter of which will communi- 
€ate the difeafe to thofe who have not been 
previoufly infected. ee 
XIV. “‘ That, although it is difficult to 
determine precifely the number di exceptions 
to the practice, the Medical Council are fully 
€onvinced, that the failure of vaccination, 
as a preventive of the fmall-pox, is a very 
rare occurrence. 
XV. <¢ That of the immenfe number who 
have been vaccinated in the army and navy, 
in different parts of the United Kingdom, and 
im every quarter of the globe, fcarcely any 
infantes of fach failure have been reported 
to the Committee, but thofe. whico are faid 
fo have occurred in the metropolis, or iis 
Vicinity! NP sid 
MVI. “* That the Medical Council are fully 
affured, that in very many places, in which 
the fmall-pox raged with great violence, the 
difeafe has been ipeedily and eftectuaily ar- 
refed ia its progrefs, and in ome populous 
[Feb. 1, 
cities almoft wholly exterminated, by the 
practice of vaccination. 
AVI. “ That the practice ef inoculation 
for the fmall-pox, on its firft introduétion in- 
to this country, was oppofed and very much 
retarded, in confequence of mifreprefentations 
and arguments drawn from affumed faéts, and 
of mifcarriages arifing fromthe want of correét, 
information, fimilar to thofe now brought for- 
ward againft vaccination, fo that nearly fifty 
years elapfed before fmall-pox inoculation was 
fully eftablifhed. 
XVIII. “* That, by a reference to the bills 
of mortality, it will appear that, to the un- 
fortunate negleét of vaccination, and to the 
prejudices raifed againft it, we may, in a 
great meafure, attribute the lofs of nearly two 
thoufand lives by the fmall-pox, in this me- 
tropolis alone, within tue prefent year. 
XIX. “ That the few inftances of failure, , 
either in the inoculation of the COW-pox, or 
of the fmall-pox, ‘ouzht not to be confidered 
as objections to either pra@tice, but merely 
as deviations from the ordinary courfe of na- 
ture. 
XX. 6 That, feem all the fas which’ 
they have been able to colleét, it appears to 
the Medical Council, that the cow-pox is ge- 
nerally mild and harmilefs in its effeéts; and 
no inftance has come to their knowledge, in 
which there was reafon to admit that vaccine 
inoculation had, of .itfelf, produced any new 
or dangerous diieafe, as has been ignorantly 
and unwarrantaoly afferted ; but that the few 
caies which have heen alleged againft this 
opinion, may be fairly attributed to other 
caufes. 
XXL. « That ifa comparifon be made be= 
tween the effects of vaccination, and thofe of 
inoculation for the fmall-pox, it would be 
neceflary to take into account the’ gréater 
number of perions who have been vaccinated’ 
within a given time, it being probable that 
within .the. lait fevyen years, nearly as many 
perfons have been inoculated for the cow-pox,- 
as were ever inoculated for the fmall-pox, 
fince the practice was introduced into this 
kingdom. 
XXL. <* That many well-knowncutaneous 
difeafes, and fome fcrophulous complaints, 
have been yeprefented as the effects of vaccine 
inoculation, when in ia¢t they originated from 
other caufes, and in many inftances occurred 
long after vaccination ; but that fuch difeafes. 
“are infinitely lefs frequent aftef vaccination,’ 
than after either the natural or inoculated 
{imall-pox.” 
Mr. JoHn Mann, of Bradford, has in- 
vented a muficai inftrument, upon an en- 
tirely new conftruétion, which he calls the 
Orcheftrino. Its oucward appearance re. 
fembles the grand horizontal piano-forte ; 
but the brilliant power, and richnefs of its 
tones, ftand unrivalled by any ftringed 
inftrument played with keys: it has the 
power of retaining the found ter any length, 
Q 
a 
