1805.] 
himfelf, even the common or flighteft pre- 
tenfions to the name wf vaccination. Ex- 
clufive pretenfions to extraordinary (kill 
or knowledge in this particular, are vain 
in the extreme. Every one is competent 
to the bufinefs, who is in the habit of c2re- 
ful and minute objervation of the appear- 
ances of difeafe in the human frame, and 
who will befow upon the fubjeét a vigi- 
Jant and patient attention. The larger 
his experience, undoubtedly, the greater 
will be his opportunities of obferving 
thofe anomalies which occafionally thew 
themfelves, and frem which, at the pre- 
fent time, more than from its ordinary 
charaHers, our improved acquaintance 
with the fubje& may be expected to arife. 
The friends of vaccination appear to have 
erred in confidering the who'e affair as 
already and perte¢tly underftood; and 
confeyuently relaxi:g in thofe attentions 
to the appearances and progre{s of the fe- 
veral cales as they fucceffively pafs in re- 
view, by which alone any defeétive parts 
of its hiftory may yet be elucidated ; ir- 
regular appearances alcettained and com- 
pared; errors in praftice deteéted; and 
the value and importance of this ine#tima- 
ble difcovery, both as a mean of proteét- 
ing individuals, and of refcuing the human 
race from thedefolarions of the moft dread- 
ful of difeafes, piaced beyond the reach 
even of cavil or cbieétion. 
For the fatistaStion of thofe who are 
not familiar with the irregularities and 
failures which occafionally take place in 
the inoculation of {mail pox, and even in 
the effeéts of the natural difeafe, I fhall 
fubjoin an account of the following nine 
cafes, which, except the firt, have oc- 
cured, more or Jels, immediately within 
my own knowl-dge; and to which many 
‘others might be added from the works of 
different authors on the fubje&t. In re- 
citing them, I have, for the moft part, 
ufed initials inftead of the names at length, 
not having afked the authority of the par- 
ties for making them public. Any per- 
fons defirous of farther particulars will 
find me always ready to anfwer their in- 
quiries. 
Cafe 1.—As a mof ftriking intance of 
the occurrence of {mall pox twice to the 
fame perion, I thal, firft of all, adduce the 
‘well known cafe of Mr. Richard Lang- 
ford, a tarmer, of Welt S5efford, in Berk- 
thire, which is recorded by Mr. Edward 
Withers, of Newberry, and publifhed in 
the fourth volume of the Memoirs of the 
Medicai Society of London. Mr. Lang- 
ford had pafled though the difeafe in his 
infancy, when three others of the family 
were alfo alfected by it, ane of whom died. 
Mr. Addington on Vaccination. 509 
His face was fo remarkably pitted and 
feamed, as to attraét general notice, and 
no one who faw him entertained a doubt 
of his having had the difeafe in a moft in- 
veterate manner. It was the cuftom of 
this gentleman, it feems, from his fympa- 
thy with perfons affliéted with fmall pox, 
to vifit and affift the poor when labouring 
under its vifitations; and in the month 
of May, 1775, he again took the infec- 
tion, and, on the twenty-firft day from the 
feizure, feli a facrifice to it. Two phy- 
ficians, Dr. Collet and Dr. Hulbert, con- 
curied with Mr. Withers in opinion of 
the fecond difeafe being truly fmall-pox, 
which was ftill farther confirmed by others 
of the family afierwards falling ill of ic— 
to one more of whom (a filter of the de- 
ceafed) it alfo proved facal. 
Cafe 2.—The fecond cafe is of very re- 
cent occurrence. Not longer ago than the 
8th of OStobcr laft, I vifited the daughter 
of Mr. C. of Rufflel-(quare, Bloomfbury, 
who was then recovering from a mott fe. 
vere and dzngerous form of confluent 
imall-poz, by which her life had been 
brought into the moft imminent danger, 
This child had been inoculated for {mall- 
p°x, on the 14th of November, 1301, and 
pafled througn the difea‘e with all its ufual 
chara¢ters, both as tothe lccal affeétion 
in the inoculated arm, where it had left 
the common fear, and the conftitutional 
diteafe. She liad the eruprive fever at the 
proper time, a convulfion-fit, and four or 
five puftules about the face, which ma- 
turated and declined with perfe&t regu- 
larity. 
In recalling the hifory of inoculations 
performed many years ago in the ordinary 
routine of prattice, where notes were not 
made at the time, it 13s not often that the 
feveral particulars of any cafe can be fo 
cleariy made out as to come ftriétly within 
the nature of evidence. In the want of 
this, it is, I think, amply fufficient to our 
purp ic, if it can be fhewn that the fuc- 
cefs of the procefs w2s fuch as to give full 
fatisfaétion to 2 practitioner deemed com- 
petent to his bufinefs, and a fenfe of com- 
plete fecurity to the mind of the patient or 
his triends. Of this defcription are the 
two following :-— 
Cafe 3—Mrs. R_a lady whof child I 
very iately vaccinated, informed me that 
her own father ceitainly had the fmall 
pox twice. The particulars are as fol- 
lows: Mr. D. of C. in Devonhhire, then 
of adulr age, had paffed through the {malli- 
pox in his childhood. That he was con- 
fidered by himfclf, by his family, and by 
the medical attendant, to be perfectly fe~ 
cure, will plainly appear, from the man- 
ner 
