Aas organizational-cum-administrative and quarantine measurese 
The second zone contained six districts where foot-and-mouth 
disease first occurred in December 1965 - January, 1966. In all 
these districts, the cattle underwent vaccination in combination 
with quarantine measures at the very beginning of the outbreak. 
In the third zone there were seven districts situated (with 
the exception of the Odesaa district ) in the western part of the 
republic. In these districts the epizootics broke out mainly in 
February - March, 1966. The cattle received prophylactic foot-and- 
mouth disease vaccination even before the main outbreak of the 
disease. 
The regions of Ivano-Frankovska and Zakarpatia were free of 
foot-and-mouth disease in the period of 1965 - 1966. The efficacy 
of vaccination was estimated according to the opinion of many epi- 
zootiologists, who stated that an epizootic was over if 85% of the 
susceptible animals were immune. 
In the first zone (Figure 1) where the foot-and-mouth 
disease type Ap> had good chances of spreading before vaccinations 
began, the efficacy of vaccination was low because of the delay in 
vaccinations. 69.3% of all the affected foci fell in this region 
with 74.6% of cattle having been affected in the entire republic. 
A sharp fall in the epizootics in this zone was marked 1.5 
months earlier than shown by theoretical calculations and they 
were over in 7 months after beginning with over 60% animals having 
become immune as a result of pulling over or vaccination. 
In the second zone (Figure 2) owing to large-scale and very 
early use of prophylactic vaccination, 79.1% of cattle escaped 
being affected by foot-and-mouth disease. In this group an animal 
that did not fall sick had received 1.9 shots of anti-foot-and- 
mouth disease vaccine. 
22.4of all the affected foci fall in this group with 20.% 
of cattle that suffered from foot-and-mouth disease in the course 
of the epizootics. The factual period of the epizootics coming to 
an end was a month later than the calculated data, 100% of the 
animals being immune. 
Le 
